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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STK3
All Species:
54.24
Human Site:
Y221
Identified Species:
91.79
UniProt:
Q13188
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13188
NP_006272.2
491
56301
Y221
M
A
E
G
K
P
P
Y
A
D
I
H
P
M
R
Chimpanzee
Pan troglodytes
XP_528201
562
64309
Y292
M
A
E
G
K
P
P
Y
A
D
I
H
P
M
R
Rhesus Macaque
Macaca mulatta
A4K2T0
487
55587
Y224
M
A
E
G
K
P
P
Y
A
D
I
H
P
M
R
Dog
Lupus familis
XP_532280
491
56230
Y221
M
A
E
G
K
P
P
Y
A
D
I
H
P
M
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9JI10
497
56837
Y221
M
A
E
G
K
P
P
Y
A
D
I
H
P
M
R
Rat
Rattus norvegicus
O54748
491
56103
Y221
M
A
E
G
K
P
P
Y
A
D
I
H
P
M
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518508
281
31761
S52
H
V
V
K
Y
Y
G
S
Y
F
K
N
T
D
L
Chicken
Gallus gallus
Q5ZJK4
486
55318
Y223
M
A
E
G
K
P
P
Y
A
D
I
H
P
M
R
Frog
Xenopus laevis
Q6IP06
493
56486
Y220
M
A
E
G
K
P
P
Y
A
D
I
H
P
M
R
Zebra Danio
Brachydanio rerio
Q7ZUQ3
492
56062
Y220
M
A
E
G
K
P
P
Y
A
D
I
H
P
M
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8T0S6
669
75091
Y236
M
A
E
G
K
P
P
Y
G
E
I
H
P
M
R
Honey Bee
Apis mellifera
XP_393691
465
52970
Y217
M
A
E
G
K
P
P
Y
G
D
I
H
P
M
R
Nematode Worm
Caenorhab. elegans
Q9NB31
497
55620
Y229
M
A
E
G
R
P
P
Y
S
D
I
H
P
M
R
Sea Urchin
Strong. purpuratus
XP_781787
488
55060
Y221
M
A
E
G
K
P
P
Y
A
E
I
H
P
M
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.8
78.6
99.3
N.A.
95.7
96.7
N.A.
53.1
79.4
93.7
89.4
N.A.
46.1
66.4
51.5
64.9
Protein Similarity:
100
86.8
89.8
99.5
N.A.
97.1
98.3
N.A.
56.4
88.1
96.3
93.5
N.A.
58.5
75.5
67
78.6
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
100
100
100
N.A.
86.6
93.3
86.6
93.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
6.6
100
100
100
N.A.
93.3
93.3
100
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
93
0
0
0
0
0
0
72
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
79
0
0
0
8
0
% D
% Glu:
0
0
93
0
0
0
0
0
0
15
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
93
0
0
8
0
15
0
0
0
0
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
93
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
93
0
0
0
0
% I
% Lys:
0
0
0
8
86
0
0
0
0
0
8
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% L
% Met:
93
0
0
0
0
0
0
0
0
0
0
0
0
93
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
93
93
0
0
0
0
0
93
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
93
% R
% Ser:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% T
% Val:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
8
0
93
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _